Cell lines derived from human tumoral primary cells are widely used in scientific research. We have almost 200 cell lines models most of which have been tested for their capacity to grow as subcutaneous xenografts in immunodeficient mice.

Our approval for animal experimentation allows us to implant those models in SCID CB17, athymic Nude, NOD-SCID, or CEIA NOG mice. If your model requires another strain of immunodeficient mice, we can make an amendment to our authorization within a few weeks. Our preferred strain is the SCID CB17 mice, as they allow an efficient but not too aggressive tumour uptake and their residual immune system is convenient to determine the antitumor efficacy of therapeutic antibodies.

Liquid tumours in Xenograft models

In vitro cultivated human cell lines are implanted into immunodeficient mice to create Cell line-Derived Xenograft (CDX) models, which are used to assess the effectiveness of potential
cancer treatments.
At Antineo, our liquid human cancer cell lines are available for subcutaneous or intravenous implantation. They may be monitored via bioluminescent imaging, routine blood collection,
and flow-cytometry detection of specific markers.
Antineo provides a wide range of liquid tumors in xenografts models, from Acute Lymphoblastoid Leukemia models to Burkitt’s Lymphoma or Diffuse Large B Cells Lymphoma models.

Acute Lymphoblastoid Leukemia, B cells

  • RS4;11 (View PDF)
  • 697 (On request)

Acute Lymphoblastoid Leukemia, B cells

  • CCRF-CEM (View PDF)
  • JM (View PDF)
  • Jurkat (On request)
  • Molt-4 (On request)
  • Reh (On request)

Acute Myeloid Leukemia

Chronic Lymphocitic Leuke mia, B cells

  • MEC1 (View PDF)
  • BV-173 (On request)

Burkitt's Lymphoma

  • Daudi (View PDF)
  • Ramos (View PDF)
  • Raji (View PDF)
  • EB2 (On request)
  • NaMalwa (On request)

Diffuse Large B Cells Lymphoma

Follicular Lymphoma

  • RL (View PDF)
  • DOHH2 (On request)

Mantle Cells Lymphoma

Myeloma

Cutaneous T lymphoma

  • Myla (View PDF)
  • HUT-78

Solid tumours in Xenograft models

Bladder cancer

ScaBER
On request
5637
On request
T24
On request
J82
On request
RT4
On request

Breast cancer

MCF7
Download PDF
HCC1806
Download PDF
BT474
Download PDF
DU4475
Download PDF
MDA-MB-157
On request
MDA-MB-175
On request
MDA-MB-231
Download PDF
MDA-MB-361
On request
MDA-MB-436
On request
MDA-MB-453
On request
MDA-MB-468
On request
BT549
On request
JIMT-1
On request
SK-BR-3
On request
CAMA-1
On request
T47D
On request
ZR-75-1
On request

Colorectal cancer

HCT 116
Download PDF
HT-29
Download PDF
Isreco-1
Download PDF
SW620
Download PDF
COLO 320
On request
Isreco-3
On request
SW403
On request

Esophagus cancer

Kyse-150
Download PDF
OE19
Download PDF

Gastric cancer

SNU-5
Download PDF
Hs746T
Download PDF
NCI-N87
On request

Glioblastoma

U251
Download PDF
T98G
On request
U-87
Download PDF
ADF
On request

Head and Neck cancer

FaDu
Download PDF
HN097
Download PDF
CAL-27
Download PDF
BICR 18
Download PDF
BICR 22
On request
BICR 56
On request
DETROIT562
On request
H357
On request

Hepatic cancer

HepaRG
On request
HepG2
On request

Lung cancer

A549
Download PDF
NCI-H292
Download PDF
NCI-H596
On request
NCI-H1703
On request
NCI-H1975
Download PDF
HCC-78
On request
HCC95
On request
HCC827
On request
SK-MES-1
On request
MSTO-211H (Pleural Biphasic Mesothelioma)
On request
ISTMes2 (Pleural Epithelioid Mesothelioma)
On request

Melanoma

A2058
Download PDF
MeWo
Download PDF
MEL Juso
Download PDF
Colo 829
Download PDF
SK-MEL-2
On request
SK-MEL-5
Download PDF
SK-MEL-24
On request
Malme-3
On request
A-375
On request
HMCB
On request
Hs940T
On request
IGR39
On request

Neuroblastoma cancer

SH-SY5Y
On request

Ovarian cancer

A2780
Download PDF
SK-0V-3
Download PDF
OV-90
Download PDF
OV-CAR-3
Download PDF
PA-1
Download PDF
Cov434
On request
AG6000
On request
TOV-112D
On request

Pancreatic cancer

Capan-1
Download PDF
Colo 357
Download PDF
MIA PaCa-2
Download PDF
BxPC-3
On request
Panc-1
On request

Prostate cancer

DU145
Download PDF
PC3
Download PDF
LNCaP
On request

Sarcoma

SK-LMS-1
Download PDF
A-673
On request
MES-SA
On request

Contact our Team to learn more

Contact