Antineo: Pancreas Adenocarcinoma Tumour model – Panc02
▪ Panc02 cells
Mouse Panc02 is a well-established mouse pancreatic ductal adenocarcinoma (PDAC) model
developed by chemical induction with 3-methylcholanthrene (3-MCA).
▪ Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of
C57/Bl6 mice. The resulting tumours were monitored by measuring two diameters with calipers, and
extrapolating the volume to a sphere.
The mice bearing Panc02 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or
subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (View PDF)
Tumour growth curve of the Panc02 cells as subcutaneous tumors Mean ± SEM (n=6; take rate 100%)