Antineo : Non Hodgkin’s Lymphoma tumour model – ES-moult
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ES-moult cells
Human Granta cells were isolated from a patient with non-hogkin’s lymphoma
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing ES-moult tumours can be treated by intra-peritoneal, intra-venous, intratumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (View PDF)
Tumour growth curve of the ES-moult cells as xenograft Mean ± SEM (n=3; take rate 100%)
Antineo can also perform an intra-medullar implantation.