Antineo: Skin Melanoma Tumour model - Yumm1.7
Yumm1.7 cells
Mouse Yumm1.7 cells were isolated from the skin of an adult mouse with melanoma.
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of C57Bl/6 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
or subcutaneous injection of the compounds. Per os administration is also possible.
The mice bearing Yumm1.7 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral
- Figure 1: (view PDF)
Tumour growth curve of the Yumm1.7 cells as subcutaneous tumors Mean ± SEM (n=8; take rate 100%)