Antineo : Skin Melanoma Tumour model – Colo 829
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Colo 829 cells
Human Colo 829 cells were isolated from the skin of patient with melanoma.
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of Nude mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing Colo 829 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (View PDF)
Tumour growth curve of the Colo 829 cells as subcutaneous tumors Mean ± SEM (n=4; take rate 100%)
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