Antineo : Skin melanoma Tumour model – A2058
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A2058 cells
Human A2058 cells were isolated from a amelanotic melanoma.
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing A2058 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1:(View PDF)
Tumour growth curve of the A2058 cells as subcutaneous tumors Mean ± SEM (n=5; take rate 100%)