We offer state-of-the-art technologies for sample characterisation, enabling detailed analysis of complex biological effects. Our platforms and expertise allow us to guide your research and development from preclinical to clinical. We will help you caracterize your samples, with a focus on precision and quality results.

Multiple colour flow cytometry

To provide comprehensive and quantitative multiparametric studies, we use state-of-the-art flow cytometry technologies, such as the BD™ LSRFortessa and BD™ Canto™ flow cytometers, as well as the CYTEK Aurora™ for spectral flow cytometry. We can then detect and quantify multiple cellular markers at once, providing important information on cell populations and their characteristics. We frequently carry out a variety of flow cytometry experiments, including:

Immunophenotyping:

In-depth examination of immune cell populations that allows for a characterization of cell surface indicators, activation conditions, and stages of differentiation.

Functional studies:

By combining flow cytometry with functional assays (for example cytokine production, apoptosis, or cell proliferation assays), we are able to assess cellular responses to treatments or environmental conditions.

Data analysis:

We use FlowJo® LLC software for advanced data analysis, providing sophisticated tools for gating, clustering, and visualising complex data sets.

High throughput sequencing

We provide high-throughput sequencing services through ProfileXpert genomic platform and our partnership with Parean Bio, offering a broad range of sequencing technologies. This includes next-generation sequencing (NGS), which allows for high-precision analysis of genomic and transcriptomic profiles, to better understand genetic variations, gene expression, or mutation landscapes :

Whole genome sequencing (WGS) :

For a global analysis of the genome, determining mutations, copy number variations and structural changes.

RNA-Seq :

For assessing gene expression at the transcript level, offering information on gene regulation, splicing events and differential expression in response to treatments.

Target sequencing:

Focusing on specific region of interest, such as cancer-related genes or pathways, for more cost-effective, high-resolution analysis.

Single-cell sequencing:

This technique offer a deeper understanding of cellular heterogeneity at the single-cell level, essential for studying tumor microenvironments or immune cell populations.

Molecular Biology

Our molecular biology capabilities provide a large set of experiments aimed at understanding gene and protein function, expression and regulation. We offer:

Quantitative PCR (qPCR):

For quantification of gene expression levels, enabling you to analyze gene regulation and evaluate the response to treatments.

Western Blotting:

For detection and characterization of proteins of interest, enabling us to examine protein expression or post-translational modifications.

Immunoprecipitation (IP):

For studying protein-protein interactions, post-translational modifications, and the isolation of specific proteins from complex samples, allowing to study signaling pathways and cellular processes.