Antineo : Pancreas Adenocarcinoma Tumour model – Capan-1
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Capan-1 cells
Human Capan-1 cells were isolated from a pancreas of patient with adenocarcinoma.
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing Capan-1 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1:(View PDF)
Tumour growth curve of the Capan-1 cells as subcutaneous tumors Mean ± SEM (n=6; take rate 100%)