Antineo : Head and Neck carcinoma tumour model – HNO97
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HNO97 cells
Human HNO97 cells were isolated from the mouth of a patient with H&N squamous cells carcinoma.
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing HNO97 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1:(View PDF)
Tumour growth curve of the HNO97 cells as xenograft Mean ± SEM (n=3; take rate 100%)