Antineo : Esophageal Carcinoma Tumour model – OE19
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OE19 cells
Human OE19 cells were isolated from an adenocarcinoma of gastric cardia/oesophageal gastric junction of a patient.
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing OE19 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1:(View PDF)
Tumour growth curve of the OE19 cells as subcutaneous tumors Mean ± SEM (n=3; take rate 100%)