Antineo : Duke’s C Type colorectal adenocarcinoma tumour model – SW620
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SW620 cells
Human SW620 cells were isolated from a metastasis in the lymph node of a patient with Duke’s
Type C colon adenocarcinoma.
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID-CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing SW620 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (View PDF)
Tumour growth curve of the SW620 cells as xenograft Mean ± SEM (n=3; take rate 100%) Antineo can also perform an intra-caecal implantation.