Antineo: B cells Sarcoma Tumour model – A20
A20 cells
Mouse A20 cells were isolated from a spontaneous reticulum cell neoplasm found in an old Balb/cAnN mouse.
▪ Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of Balb/cAnN mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing A20 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (view PDF)
Tumour growth curve of the A20 cells as subcutaneous tumors Mean ± SEM (n=7; take rate 100%)