Tumour model - C8161
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C8161 cells
Human C8161 cells were isolated from an abdominal-wall metastasis of a menopausal woman with recurrent malignant melanoma.
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Tumour growth in vivo
The cells were collected from a tissue culture flask and injected subcutaneously in the right flank of SCID/CB17 mice. The resulting tumours were monitored by measuring two diameters with calipers, and extrapolating the volume to a sphere.
The mice bearing C8161 tumours can be treated by intra-peritoneal, intra-venous, intra-tumoral or subcutaneous injection of the compounds. Per os administration is also possible.
Figure 1: (View PDF) Tumour growth curve of C8161 cells as subcutaneous tumors Mean ± SEM (n=6)